What this test measures
- Thyroid-Stimulating Hormone (TSH)From the lab
The pituitary's instruction to the thyroid, and the first number read when thyroid function is in question.
- Free T4 (FT4)From the lab
The unbound share of the thyroid's main storage hormone, which is the part available to tissues.
- Free T3 (FT3)From the lab
The unbound share of the active thyroid hormone that sets metabolic rate.
A thyroid test, often called a thyroid function test, is a blood test that shows how well your thyroid gland is working. The usual set is TSH, free T4 and free T3. Read together, they show whether the thyroid looks underactive, overactive or in balance, and they often hint at whether the cause sits in the thyroid itself or in the pituitary gland that controls it.
What the thyroid does
The thyroid is a butterfly-shaped gland in the front of the neck. Its hormones help the body use energy, stay warm and keep the brain, heart, muscles and other organs working as they should. It mainly releases thyroxine (T4). The liver and other tissues convert T4 into triiodothyronine (T3), the form that acts on cells. The pituitary gland, at the base of the brain, watches the level of thyroid hormone and releases thyroid-stimulating hormone to ask the thyroid for more when it falls, and less when it rises.
What the test includes
The test pairs the pituitary's signal with the hormones it controls. Thyroid-Stimulating Hormone (TSH) is the signal, and it is usually the opening test because a small change in thyroid hormone produces a large change in TSH, often before the hormones themselves leave their ranges. Free T4 (FT4) and Free T3 (FT3) are the unbound shares of the two thyroid hormones, the parts available to tissues. Measuring the free forms avoids the shifts in total hormone that come with pregnancy and the contraceptive pill, which raise the proteins that carry thyroid hormone. Free T3 adds most when TSH is low, because in some people with a low TSH, T3 is raised while free T4 is still normal.
Thyroid antibody tests, such as thyroid peroxidase antibodies, are separate. Doctors usually add them when TSH is raised, to look for autoimmune thyroid disease, the common cause of an underactive thyroid. They are not part of Clare's panel.
Who usually asks for one
Most thyroid tests are ordered because of symptoms. An underactive thyroid tends to slow things down: tiredness, weight gain, feeling cold, dry skin, thinning hair, heavy or irregular periods and low mood. An overactive one tends to speed things up: weight loss despite eating more, a fast or irregular heartbeat, nervousness, poor sleep and feeling hot. These symptoms are common and have many other causes, which is why the blood test matters.
In the UK, NICE recommends offering thyroid tests to people with type 1 diabetes or another autoimmune disease and to people with new atrial fibrillation (an irregular heart rhythm), and considering them in depression or unexplained anxiety. It notes that thyroid symptoms in menopausal women can be mistaken for menopause, and advises against testing someone simply because they have type 2 diabetes. People who take thyroid medicine have regular tests to check the dose, and anyone with a thyroid history who is pregnant or planning a pregnancy is advised to tell their doctor.
Preparing for the test
Thyroid tests usually need no fasting or special preparation on their own. If the same draw includes tests that need fasting, follow those instructions. Mention every medicine and supplement you take, and do not stop a prescribed medicine unless your doctor tells you to.
Biotin deserves a specific mention. It is common in hair, skin and nail supplements, and at high doses it can make some thyroid assays read falsely high or falsely low. NICE asks doctors to check biotin intake when thyroid problems are suspected, and some laboratories and the American Thyroid Association ask for a gap between the last dose and the sample, so tell the person ordering the test if you take it.
Testing during an acute illness is usually avoided, because the illness itself can shift the results. TSH also follows a daily rhythm, peaking at night and lowest between late morning and afternoon, though Mayo Clinic Laboratories notes this rarely changes how a daytime result is read.
How the results are read together
The three markers are read as a pattern. These are the common ones and what each usually points to. They are starting points for a conversation with a doctor, not diagnoses.
| Pattern | What it usually points to |
|---|---|
| TSH high, free T4 low | An underactive thyroid (primary hypothyroidism), most often autoimmune (Hashimoto's) |
| TSH high, free T4 normal | The pattern called subclinical hypothyroidism; usually confirmed on a repeat test before any decision |
| TSH low, free T4 or free T3 high | An overactive thyroid (hyperthyroidism), commonly Graves' disease or an overactive nodular thyroid |
| TSH low, free T4 and free T3 normal | The pattern called subclinical hyperthyroidism; usually repeated |
| TSH low or normal, free T4 low | A problem in the pituitary gland, or the effect of a recent serious illness |
| TSH normal or high, free T4 high | Uncommon; often a medicine, thyroid hormone treatment or interference with the assay, and rarely a pituitary or inherited cause |
| TSH and free T4 both in range | A thyroid condition is unlikely |
Two things make patterns harder to read. Illness, starvation and recovery from illness can shift all three for a while without any thyroid disease, a state called non-thyroidal illness, and T3 tends to move most. Some medicines also change thyroid function or the tests themselves, including amiodarone, lithium, heparin and biotin. For a longer walk through borderline results, read How we read a thyroid panel: TSH, free T4 and free T3.
How Clare's panel handles it
Clare's panel includes all three markers, each measured by the lab in the same blood draw. NICE describes a stepwise approach in the UK, starting with TSH and adding free T4, or free T4 and free T3, when TSH is out of range. Measuring the three together means a TSH near the edge of its range is always read beside the hormones it controls.
Why it matters in the UAE
In a study of 77,758 adults who had thyroid tests at Dubai Health primary care centres between 2018 and 2020, 2.1% had a recorded diagnosis of hypothyroidism. About four in five of them were women, and the highest rate, 2.52%, was in people aged 35 to 44. The authors note that this is similar to rates reported in Europe and North America.
Ramadan matters for people who take levothyroxine. Two UAE studies found that TSH rose in the weeks after Ramadan. In the larger one, of 481 patients at a UAE endocrine centre, median TSH went from 2.0 to 2.9 mIU/L one to two weeks after Ramadan, free T4 and free T3 fell, and all three were back in the normal range 3 to 6 months later. A thyroid test taken soon after Ramadan is read with that timing in mind.
Price in the UAE
When we read public prices on 11 October 2026, a thyroid function test (usually TSH, free T4 and free T3) cost from 99 to 300 at 6 UAE providers. Packages that add other blood tests, thyroid antibodies or a specialist consultation were listed from 499 to 1,200. VAT was rarely stated, some prices were offers, and home collection can add a fee.
Related tests
An underactive thyroid can contribute to high cholesterol, so LDL Cholesterol and the rest of a lipid profile sit naturally beside a thyroid test. An underactive thyroid is also one of the recognised causes of a raised Prolactin, the pituitary hormone that signals the body to make breast milk.
Why the results mean more over time
Each person's thyroid hormone levels stay close to their own set point, while the population ranges printed on a report are broad. A single result inside the range therefore says less than a run of results that shows whether TSH is drifting. How often doctors recheck depends on the situation. NICE suggests repeating tests no sooner than 6 weeks after the last one when symptoms change; every 3 months for adults starting thyroid medicine until TSH is stable, then once a year; and, for adults with untreated subclinical hypothyroidism, once a year if there are signs of underlying thyroid disease or every 2 to 3 years if not. Clare is opening with a waitlist at clare.health.
- American Thyroid Association, Thyroid function tests (accessed 2026) https://www.thyroid.org/thyroid-function-tests/
- American Thyroid Association, Hypothyroidism (accessed 2026) https://www.thyroid.org/hypothyroidism/
- NICE, Thyroid disease: assessment and management, NG145 (2019, updated 2023) https://www.nice.org.uk/guidance/ng145/chapter/Recommendations
- MedlinePlus, TSH (thyroid-stimulating hormone) test (accessed 2026) https://medlineplus.gov/lab-tests/tsh-thyroid-stimulating-hormone-test/
- MedlinePlus, Thyroxine (T4) test (accessed 2026) https://medlineplus.gov/lab-tests/thyroxine-t4-test/
- MedlinePlus, Triiodothyronine (T3) tests (accessed 2026) https://medlineplus.gov/lab-tests/triiodothyronine-t3-tests/
- MedlinePlus, Hypothyroidism (accessed 2026) https://medlineplus.gov/hypothyroidism.html
- MedlinePlus, Prolactin levels (accessed 2026) https://medlineplus.gov/lab-tests/prolactin-levels/
- Koulouri O, Gurnell M, How to interpret thyroid function tests, Clinical Medicine (2013) https://pmc.ncbi.nlm.nih.gov/articles/PMC5922674/
- Koulouri O et al., Pitfalls in the measurement and interpretation of thyroid function tests, Best Pract Res Clin Endocrinol Metab (2013) https://pmc.ncbi.nlm.nih.gov/articles/PMC3857600/
- Mayo Clinic Laboratories, STSH Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum (accessed 2026) https://www.mayocliniclabs.com/test-catalog/overview/8939
- Gloucestershire Hospitals NHS Foundation Trust, Thyroid function tests (TSH, FT4, FT3) (2026) https://www.gloshospitals.nhs.uk/our-services/services-we-offer/pathology/tests-and-investigations/thyroid-function-tests-tsh-ft4-ft3/
- Li D et al., Association of biotin ingestion with performance of hormone and nonhormone assays in healthy adults, JAMA (2017) https://pmc.ncbi.nlm.nih.gov/articles/PMC5818818/
- Abdulla S et al., Prevalence of hypothyroidism among patients undergoing thyroid function tests in primary healthcare centres in Dubai, UAE, BMC Public Health (2025) https://pmc.ncbi.nlm.nih.gov/articles/PMC12465217/
- Alkaf B et al., Ramadan fasting and changes in thyroid function in hypothyroidism: identifying patients at risk, Thyroid (2022) https://pubmed.ncbi.nlm.nih.gov/35152772/
- El-Kaissi S et al., Impact of lifestyle changes during Ramadan on thyroid function tests in hypothyroid patients taking levothyroxine, Endocrine Practice (2020) https://pubmed.ncbi.nlm.nih.gov/33471643/
- Valeo Health, Thyroid Function, AED 99, price read 11 October 2026 https://www.feelvaleo.com/en-ae/dubai/services/thyroid-function
- Health 24/7, Thyroid Function Test, AED 300, price read 11 October 2026 https://health247group.ae/blood-test-at-home-dubai/
- Aster (myAster), Thyroid Health Package, AED 499, price read 11 October 2026 https://www.myaster.com/en/health-hub/packages/p/thyroid-health-package/145
- NMC Healthcare, Metabolic and Thyroid Health package, AED 1,200, price read 11 October 2026 https://nmc.ae/en/health-packages/specialised-health-packages
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