What this test measures
- Hemoglobin A1c (HbA1c)From the lab
The share of hemoglobin with sugar attached to it, which tracks average blood sugar over about three months.
- Fasting GlucoseFrom the lab
Blood sugar measured on a fasting sample, so the figure reflects the baseline rather than the last meal.
- Fasting InsulinFrom the lab
The hormone that moves sugar out of the blood, measured on a fasting sample.
- HOMA-IRDerived biomarker
Fasting insulin and fasting glucose combined into a single estimate of insulin resistance.
- TyG IndexDerived biomarker
Triglycerides and fasting glucose combined on a logarithmic scale, a second estimate of insulin resistance.
- Estimated Average Glucose (eAG)Derived biomarker
HbA1c restated as an average blood sugar, in the units a glucose meter reads.
A diabetes test is a set of blood tests that shows how your body handles sugar. At its core are HbA1c, which reflects average blood sugar over the past two to three months, and fasting glucose, which shows the level on one morning. Fuller panels add fasting insulin and calculated estimates of insulin resistance. Together they are used to screen for prediabetes and type 2 diabetes, and to show the body working harder to control glucose before glucose itself changes.
What the test includes
The markers fall into three groups.
Glucose now and over months
Hemoglobin A1c (HbA1c) is the share of haemoglobin with glucose attached, a weighted average of roughly the last two to three months that needs no fasting. Fasting Glucose is blood sugar after at least 8 hours without food. The American Diabetes Association (ADA) accepts either for screening and diagnosis, and each covers a blind spot in the other: glucose varies a lot from day to day, while HbA1c can be pushed up or down by anything that changes red blood cells.
How hard insulin is working
Fasting Insulin shows how much insulin it takes to hold glucose at its fasting level. HOMA-IR combines fasting insulin and fasting glucose into one estimate of insulin resistance. The TyG Index estimates the same thing from triglycerides and fasting glucose, with no insulin result needed.
The same result in other units
Estimated Average Glucose (eAG) restates HbA1c as an average glucose in mmol/L or mg/dL, the units a glucose meter shows.
In Clare's panel, HbA1c, fasting glucose and fasting insulin are measured by the lab. HOMA-IR, the TyG Index and eAG are calculated by Clare from those results and from the triglycerides measured in the same panel.
Who usually asks for it
The ADA recommends screening all adults from age 35, and earlier for adults with overweight or obesity (a BMI of 25 or more, or 23 or more for people of Asian ancestry) who have another risk factor: a parent or sibling with diabetes, high blood pressure, low HDL cholesterol or high triglycerides, polycystic ovary syndrome, physical inactivity or a history of heart disease. People with prediabetes are usually retested yearly, and women who had diabetes in pregnancy every 1 to 3 years.
It is also requested when someone has symptoms of high blood sugar, such as unusual thirst, passing urine often, weight loss without trying, blurred vision or slow-healing sores, and to follow blood sugar in people already diagnosed.
How to prepare
HbA1c on its own needs no preparation. Fasting glucose needs at least 8 hours without food or drinks other than water, and fasting insulin 8 to 12 hours, so a panel with either is usually taken in the morning after an overnight fast.
Tell the person taking the sample if you are pregnant, have had recent blood loss or a transfusion, have anaemia, a kidney condition or a known haemoglobin trait, use insulin or other diabetes medicines, or take biotin. Each can change how one of the results should be read.
How the results are read together
None of these numbers is read alone. These are the patterns a doctor typically looks for, as patterns rather than diagnoses.
- HbA1c and fasting glucose agree. When both sit in the usual range, the picture is consistent. When both are raised, the ADA counts two abnormal results from different tests on the same sample as confirmation, so the pair carries more weight than either alone.
- HbA1c and fasting glucose disagree. The ADA suggests repeating the abnormal test and looking for a reason, such as iron deficiency, anaemia, a haemoglobin variant or how the glucose sample was handled.
- Normal glucose, high insulin. MedlinePlus describes this as the body making extra insulin because cells respond less well: the pattern of insulin resistance. HOMA-IR and the TyG Index put a number on it.
- Low glucose with high or normal insulin. This raises a different question, about too much insulin, and a doctor usually adds C-peptide and proinsulin.
- High glucose with low insulin. This suggests the pancreas is not making enough insulin.
The article HbA1c, glucose and insulin: reading them together goes through these patterns in more depth.
Estimated Average Glucose (eAG)
eAG translates HbA1c into an average glucose. It comes from the ADAG study, which compared HbA1c with about 2,700 glucose readings per person over three months in 507 people with and without diabetes. The equations are eAG (mmol/L) = 1.59 × HbA1c (%) - 2.59, and eAG (mg/dL) = 28.7 × HbA1c (%) - 46.7.
| HbA1c (%) | HbA1c (mmol/mol) | eAG (mmol/L) | eAG (mg/dL) |
|---|---|---|---|
| 5 | 31 | 5.4 | 97 |
| 6 | 42 | 7.0 | 126 |
| 7 | 53 | 8.6 | 154 |
| 8 | 64 | 10.2 | 183 |
On the same equations, an HbA1c of 5.7% corresponds to an eAG of about 6.5 mmol/L (117 mg/dL), and 6.5% to about 7.7 mmol/L (140 mg/dL).
eAG is an estimate with a wide margin. In the ADA's table, the 95% range around an eAG of 7.0 mmol/L (an HbA1c of 6%) runs from 5.5 to 8.5 mmol/L, so eAG will not always match a meter or a fasting result. Diagnosis uses HbA1c and glucose, not eAG.
TyG Index
The TyG Index estimates insulin resistance from fasting triglycerides and fasting glucose, both in mg/dL: TyG = ln(triglycerides × glucose ÷ 2), where ln is the natural logarithm. Triglycerides of 150 mg/dL and glucose of 100 mg/dL, for example, give ln(7,500), about 8.92.
It was developed in Mexico partly because an insulin test is expensive and not available in every laboratory. A 2010 study compared it with the euglycaemic clamp, the reference method for insulin resistance, and found high sensitivity and specificity. Both inputs are fasting values, so the index assumes a proper fast.
There is no agreed cut-off. Published values depend on the population and on which version of the formula a study used.
| Study population | Proposed TyG cut-off |
|---|---|
| Qatar Biobank adults, all | 8.281 |
| Qatar Biobank, men | 8.416 |
| Qatar Biobank, women | 8.168 |
| Polish adults | 8.741 |
| Mexican and Hungarian studies, on a different scale | 4.68 and 4.69 |
In the Qatar Biobank, the TyG Index had the highest accuracy of the seven insulin resistance indices compared, which makes it a useful cross-check on HOMA-IR.
Why it matters in the UAE
The International Diabetes Federation estimates that in 2024, 20.7% of UAE adults aged 20 to 79 had diabetes and 17.0% had impaired fasting glucose (both age-standardised), and that around 64% of adults with diabetes had not been diagnosed. The ADA notes that type 2 diabetes develops gradually and often has no clear symptoms in its early stages, which is why it is screened for with blood tests rather than found through symptoms.
Two other local facts affect how results are read. Inherited haemoglobin conditions are common: a 2017 review put the beta-thalassaemia carrier rate in the UAE at 8.5%, and premarital screening has been mandatory since 2012. Thalassaemia and haemoglobin variants can shift HbA1c with some methods, which is one reason to read it with fasting glucose. And the insulin resistance cut-offs proposed for Gulf populations sit below many published elsewhere.
Price
When we read public prices on 11 October 2026, an HbA1c test on its own cost from 45 to 149 at 3 UAE providers, and a diabetes panel combining HbA1c with fasting glucose, and in some cases fasting insulin, HOMA-IR or other tests, cost from 99 to 299 at 5 providers. VAT was rarely stated, several were offer or indicative prices, the dearer panels bundled a doctor's consultation, and home collection can add a fee.
Related tests
The Lipid profile supplies the triglycerides behind the TyG Index, along with the HDL cholesterol the ADA lists as a diabetes risk factor. The Iron and ferritin test and the CBC blood test help explain an HbA1c that does not fit the glucose results. For what a full panel involves on the day, see Comprehensive blood test in Dubai: what to expect.
Reading it over time
One diabetes test gives a starting point. The ADA suggests repeating screening at least every three years when results are normal, sooner if weight or other risks change, and yearly with prediabetes. HbA1c reflects roughly the last two to three months and varies little from day to day, while fasting insulin and HOMA-IR vary considerably from week to week, so the useful comparison is the same tests, after the same fast, months apart.
Clare is opening with a waitlist at clare.health.
- American Diabetes Association Professional Practice Committee, 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes 2026, Diabetes Care 49 (Suppl 1) (2026) https://pmc.ncbi.nlm.nih.gov/articles/PMC12690183/
- American Diabetes Association Professional Practice Committee, 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes 2026, Diabetes Care 49 (Suppl 1) (2026) https://pmc.ncbi.nlm.nih.gov/articles/PMC12690178/
- MedlinePlus (US National Library of Medicine), Hemoglobin A1C (HbA1c) Test (2025) https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/
- MedlinePlus (US National Library of Medicine), Blood Glucose Test (2024) https://medlineplus.gov/lab-tests/blood-glucose-test/
- MedlinePlus (US National Library of Medicine), Insulin in Blood Test (2026) https://medlineplus.gov/lab-tests/insulin-in-blood-test/
- National Glycohemoglobin Standardization Program (NGSP), Factors that Interfere with HbA1c Test Results (updated 2026) https://ngsp.org/factors.asp
- Nathan DM et al., Translating the A1C assay into estimated average glucose values, Diabetes Care (2008) https://pmc.ncbi.nlm.nih.gov/articles/PMC2742903/
- Simental-Mendía LE et al., The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects, Metabolic Syndrome and Related Disorders (2008) https://doi.org/10.1089/met.2008.0034
- Guerrero-Romero F et al., The product of triglycerides and glucose, a simple measure of insulin sensitivity: comparison with the euglycemic-hyperinsulinemic clamp, Journal of Clinical Endocrinology and Metabolism (2010) https://doi.org/10.1210/jc.2010-0288
- Aliyu U, Toor SM et al., Evaluating indices of insulin resistance and estimating the prevalence of insulin resistance in a large biobank cohort (Qatar Biobank), Frontiers in Endocrinology (2025) https://pmc.ncbi.nlm.nih.gov/articles/PMC12104043/
- Carobene A, Kilpatrick E et al., The biological variation of insulin resistance markers: data from the European Biological Variation Study (EuBIVAS), Clinical Chemistry and Laboratory Medicine (2025) https://doi.org/10.1515/cclm-2024-0672
- International Diabetes Federation, IDF Diabetes Atlas, United Arab Emirates country data (2025 edition, 2024 estimates) https://diabetesatlas.org/data-by-location/country/united-arab-emirates/
- Kim S, Tridane A, Thalassemia in the United Arab Emirates: why it can be prevented but not eradicated, PLoS ONE (2017) https://pmc.ncbi.nlm.nih.gov/articles/PMC5279727/
- Intel Lab, HbA1c, price read 11 October 2026 https://intel-lab.ae/biomarkers/hba1c
- Doctors Clinic Dubai (DCDC), HbA1c (Glycated Haemoglobin), price read 11 October 2026 https://doctorsclinicdubai.ae/blog/cheapest-blood-test-dubai
- Valeo Health, Diabetes Profile, price read 11 October 2026 https://www.feelvaleo.com/en-ae/dubai/services/diabetes-profile
- Aster (myAster), Diabetic Package Standard, price read 11 October 2026 https://www.myaster.com/en/health-hub/packages/p/diabetic-package-standard/14
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